Thermo Fisher Scientific UNC5CL Polyclonal Antibody
UNC5CL 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며 Human 및 Mouse에서 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, 장기 보관 시 -20°C에서 안정적.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 302–483 of Human UNC5CL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548391 |
Product Specific Information
- Recommended positive control: Raji
- Predicted reactivity: Human (99%), Mouse (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
UNC5CL is a membrane protein belonging to the UNC-5 family with a death domain and a ZU5 domain. It interacts with p65/RELA and NFKB1, and also with subunit p105 of NF-kappaB and transactivator p65. UNC5CL inhibits NF-kappaB activation and NF-kappaB-dependent transcription by preventing NF-kappaB from binding to its target sequence, providing an alternative regulatory mechanism for NF-kappaB-mediated transcription. This protein sensitizes cells to apoptosis induced by TNF and TRAIL.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-30917_UNC5CL_Q8IV45-1_Rabbit.svg, PA5-30917_UNC5CL_Q8IV45-1_Rabbit_PDP.jpeg)
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