
Thermo Fisher Scientific p75 NGF Receptor (extracellular) Polyclonal Antibody
p75 NGF 수용체(Extracellular) 인식 토끼 폴리클로날 항체. Western blot, IHC, Flow cytometry, IP 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 동결건조 형태. 신경세포 생존 및 분화 연구용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Flow Cytometry (Flow) | 2.5 µg |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CEEIPGRWITRSTPPE, corresponding to amino acid residues 188–203 of human p75NTR (extracellular stalk domain) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double-distilled water (DDW), depending on sample size.
- Ships as lyophilized powder at room temperature.
- Store at -20°C upon arrival.
- After reconstitution, store at 4°C (protected from light) for up to 1 week.
- For longer storage, aliquot and keep at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Neurotrophic factors regulate survival, differentiation, and maintenance of neurons in both peripheral and central nervous systems. Developing sympathetic neurons depend on nerve growth factor (NGF) during target competition in vivo. Antibodies specific to NGFR p75 are valuable tools for detecting and characterizing NGFR p75, aiding in studies of neuronal development, plasticity, and repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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