Thermo Fisher Scientific GSPT1 Polyclonal Antibody
Thermo Fisher Scientific의 GSPT1 Polyclonal Antibody는 Human, Mouse, Rat에 반응하는 Rabbit IgG 항체로, Western Blot 및 IHC(P) 실험에 적합합니다. 항원 특이적 합성 펩타이드로 면역화되었으며, 높은 순도(>95%)로 정제되어 연구용으로 사용됩니다.
- 카탈로그번호
- PA577260
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: [참고 문헌 없음]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: [참고 문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 100–150 of Human GSPT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720987 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein that belongs to the GTP-binding elongation factor family. It plays a role in regulating cell growth by controlling translation termination.
Human eRF3a shares 94% sequence identity with its mouse counterpart, indicating a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and constitutes nearly 3% of the human genome. Mutations in the GAN gene located on chromosome 16 can lead to giant axonal neuropathy, a nervous system disorder characterized by progressive malfunction with growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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