Thermo Fisher Scientific GSPT1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000
• Publications: [참고 문헌 없음]

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200
• Publications: [참고 문헌 없음]

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).

Target Information

eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein that belongs to the GTP-binding elongation factor family. It plays a role in regulating cell growth by controlling translation termination.
Human eRF3a shares 94% sequence identity with its mouse counterpart, indicating a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and constitutes nearly 3% of the human genome. Mutations in the GAN gene located on chromosome 16 can lead to giant axonal neuropathy, a nervous system disorder characterized by progressive malfunction with growth.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 없음)