Thermo Fisher Scientific PYY Polyclonal Antibody
Guinea pig 유래 polyclonal 항체로 PYY(3-36) 타겟 인식. IHC(P) 및 IHC(F)에서 1:1500~1:2500 희석으로 사용 가능. 합성 porcine peptide YY 면역원 기반. 연구용으로 식욕 조절 관련 연구에 적합. 냉장(4°C) 보관 및 -20°C 분주 보관 권장.
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Thermo Fisher Scientific PYY Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1500–1:2500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1500–1:2500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Guinea pig / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic porcine peptide YY |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
| RRID | AB_1086971 |
Product Specific Information
Reconstitute with 50–100 µL of distilled water, and dilute further in 0.1 M PBS containing 1% BSA and 0.1% sodium azide.
Once reconstituted, aliquot and freeze at -20°C.
Target Information
Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY.
It is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation.
PYY (3-36) acts as a potent inhibitor of food intake in rats and humans by selectively activating the Y2 receptor, inhibiting orexigenic NPY neurons in the arcuate nucleus, and disinhibiting anorexigenic POMC neurons.
The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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