Thermo Fisher Scientific GPX4/MCSP Monoclonal Antibody (LHM 2)
GPX4/MCSP 단클론 항체(LHM 2)는 인간, 마우스, 랫트에 반응하며 다양한 면역실험(IHC, ICC, Flow, ELISA 등)에 사용 가능. 비결합형 액상 형태로 제공되며, 4°C 보관 권장. 세포 산화 손상 보호 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg / 10^6 cells |
| ELISA | Assay-dependent |
| Immunomicroscopy (IM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LHM 2 |
| Immunogen | A375P cells crude extract (target: GPX4, UniProt ID: P36969-1, antigen range: 1–197) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione, protecting cells against oxidative damage. Human plasma glutathione peroxidase is a selenium-containing enzyme where the UGA codon is translated into selenocysteine. Alternative splicing and transcription initiation in rat result in proteins localized to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence supports alternative splicing; however, the mitochondrial and nuclear transit peptide cleavage sites require further verification.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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