
Thermo Fisher Scientific IL8 Monoclonal Antibody (1B4)
인간 IL-8 단백질을 인식하는 Mouse IgG2a 단일클론 항체로 Western blot, ELISA, IP 등에 사용 가능. 비결합형 액상 형태이며 PBS buffer에 보존. 염증 및 종양 연구용으로 적합한 고품질 연구용 항체.
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Thermo Fisher Scientific IL8 Monoclonal Antibody (1B4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 10 µg/mL |
| ELISA | 10 µg/mL |
| Immunoprecipitation (IP) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B4 |
| Immunogen | IL8 (AAH13615, 21–99 aa) full length recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
EGAVLPRSAK ELRCQCIKTY SKPFHPKFIK ELRVIESGPH CANTEIIVKL SDGRELCLDP KENWVQRVVE KFLKRAENS
Target Information
Interleukin 8 (IL-8, CXCL8) is a 72 amino acid pro-inflammatory factor belonging to the CXC chemokine subfamily.
It binds to cell surface receptors IL-8RA and IL-8RB and functions as a chemoattractant and angiogenic factor.
IL-8 expression can be induced by inflammatory stimuli in macrophages and endothelial cells, where it is stored in Weibel-Palade bodies.
IL-8 was first isolated from osteosarcoma cells and contains the ELR-motif (Glu-Leu-Arg sequence), signaling through CXCR1 and CXCR2 receptors.
Previous names include NAP-1, GCP-1, MONAP, and protein 3-10C.
IL-8 and related chemokines form a gene cluster on chromosome 4q and are implicated in tumor angiogenesis and bronchiolitis pathogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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