
Thermo Fisher Scientific PFKP Polyclonal Antibody
Thermo Fisher Scientific의 PFKP Polyclonal Antibody는 인간 PFKP 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot과 ELISA에 적합합니다. 세포질 내 PFKP 검출에 유용하며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 605–784 of human PFKP (NP_002618.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.14 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913718 |
Product Specific Information
- Positive test controls: U-87MG, HeLa, BxPC-3, Jurkat
- Subcellular location: Cytoplasm
Immunogen sequence:
IFEEPFDIRD LQSNVEHLTE KMKTTIQRGL VLRNESCSEN YTTDFIYQLY SEEGKGVFDC RKNVLGHMQQ GGAPSPFDRN FGTKISARAM EWITAKLKEA RGRGKKFTTD DSICVLGISK RNVIFQPVAE LKKQTDFEHR IPKEQWWLKL RPLMKILAKY KASYDVSDSG QLEHVQPWSV
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate signal transduction in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
The protein kinase family, comprising over 500 gene products, is one of the largest in eukaryotes and is classified into 8 major groups based on catalytic domain sequences. The AGC kinase group includes 63 kinases such as PKA, PKG, PKC, RAC/Akt, ARK, and RSK families.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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