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Thermo Fisher Scientific VAV3 Polyclonal Antibody
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Thermo Fisher Scientific VAV3 Polyclonal Antibody

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VAV3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/BSA/glycerol 완충액에 보관되며 -20°C에서 안정적으로 저장 가능합니다.

카탈로그번호
PA5143789
판매단위
pk
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마지막 업데이트 2025. 08. 05. 오후 12:35
Thermo Fisher Scientific PA5143789 VAV3 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
690,200원VAT 포함 759,220원

Thermo Fisher Scientific · Thermo Fisher Scientific VAV3 Polyclonal Antibody

Applications

Western Blot (WB)

  • Tested Dilution: 1:200
  • Publications: 없음

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen A synthetic peptide (coupled to KLH) corresponding to amino acid residues in the Dbl homology domain of human Vav3. This sequence has high homology with similar regions in rat and mouse Vav3, and low homology to other Vav family members.
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Antigen affinity chromatography
Storage buffer PBS with 1 mg/mL BSA, 50% glycerol
Contains 0.05% sodium azide
Storage conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping conditions Wet ice
RRID AB_2943017

Product Specific Information

The antibody detects a 98 kDa protein corresponding to the molecular mass of Vav3 on SDS-PAGE immunoblots of human Jurkat cells. It also strongly detects an unidentified protein at 120 kDa in Jurkat and K562 cells.


Target Information

This gene belongs to the VAV gene family. VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional changes. The gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, associating maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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