Thermo Fisher Scientific MRPL22 Polyclonal Antibody
MRPL22 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 적합. 인간, 생쥐, 랫트 반응성. 액상 형태로 1 mg/mL 농도, -20°C 보관. 연구용으로 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MRPL22 (Accession Q9NWU5), corresponding to amino acid residues A96–C146 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850794 |
Product Specific Information
Antibody detects endogenous levels of total MRPL22.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and participate in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with a protein-to-rRNA ratio of approximately 75%. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome differ among species, making sequence homology recognition difficult. The MRPL22 gene encodes a 39S subunit protein belonging to the L22 ribosomal protein family. A pseudogene is located on chromosome 4q, and two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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