Thermo Fisher Scientific MRPL24 Polyclonal Antibody
Western blot, IHC, ICC에 사용 가능한 MRPL24 폴리클로날 항체로, 인간·마우스·랫트 시료에 반응합니다. 합성 펩타이드 면역원으로 제작되었으며, 고순도의 친화 크로마토그래피 정제 항체입니다. PBS/글리세롤 완충액에 보관하며 -20°C에서 안정적입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MRPL24 (Accession Q96A35), corresponding to amino acid residues D103–I153 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850795 |
Product Specific Information
This antibody detects endogenous levels of total MRPL24.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and facilitate protein synthesis within mitochondria. Mitochondrial ribosomes consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA ratio—opposite to prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack 5S rRNA. The proteins comprising the mitoribosome vary widely across species, both in sequence and biochemical properties, making sequence homology recognition difficult. The MRPL24 gene encodes a 39S subunit protein that is more than twice the size of its E. coli counterpart. Two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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