
Thermo Fisher Scientific TRPV4 Polyclonal Antibody
TRPV4 단백질을 인식하는 Sheep 유래 Polyclonal 항체로, WB 및 IHC에 사용 가능. Rat 반응성, Lyophilized 형태로 제공되며, 4°C 단기 또는 -20°C 장기 보관 권장. TRPV4 관련 질환 연구에 적합한 연구용 항체.
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Thermo Fisher Scientific TRPV4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the cytoplasmic domain of rat TRPV4 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: TRPV4.
Target Information
TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel activated in response to systemic osmotic pressure. It functions as a non-selective calcium-permeant cation channel involved in osmotic sensitivity and mechanosensitivity.
TRPV4 belongs to the OSM9-like transient receptor potential channel (OTRPC) subfamily in the TRP superfamily. Mutations in the TRPV4 gene are associated with spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC.
Diseases associated with TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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