Thermo Fisher Scientific Human CRISP2 Synthetic Peptide
인간 CRISP2 단백질의 N-말단 15개 아미노산 서열에 해당하는 합성 펩타이드입니다. PA5-21007 항체의 블로킹 펩타이드로 사용 가능합니다. 정제된 액상 형태로 제공되며, PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide를 포함합니다. 연구용으로만 사용됩니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the amino terminus of human CRISP2.
PEP-1121 can be used as a blocking peptide with polyclonal antibody PA5-21007.
Target Information
The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility.
CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion.
CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility.
CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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