Thermo Fisher Scientific STK39 Monoclonal Antibody (OTI4H3), TrueMAB
STK39 단백질을 인식하는 Mouse IgG2b 단클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. Lyophilized 형태로 제공되며, 고순도 Affinity chromatography 정제. 세포 스트레스 반응 연구 및 혈압 조절 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H3 |
| Immunogen | Full length human recombinant protein of human STK39 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
STK39 (STLK3) is involved in the cellular stress response pathway. It is activated under hypotonic stress, leading to phosphorylation of cation-chloride co-transporters. STK39 also activates the p38 MAP kinase pathway, with reduced interaction during stress. It functions as an intermediate in stress response and is an independent risk factor for hypertension in men, with intragenic SNPs contributing to blood pressure regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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