Thermo Fisher Scientific HSP90AB1 (HSP90) Monoclonal Antibody (OTI4C10), TrueMAB
HSP90AB1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI4C10). Western blot에 최적화되어 있으며 Human, Mouse, Rat, Dog에 반응. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C10 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human HSP90AB1 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat.
HSP90 is a 90 kDa protein induced under stress conditions but also abundantly present under non-stress conditions.
HSP90 proteins are highly conserved molecular chaperones involved in signal transduction, protein folding, degradation, and morphologic evolution.
They associate with cochaperones and stabilize or refold denatured proteins after stress.
HSP90 interacts with intracellular proteins such as steroid receptors, actin, tubulin, aryl hydrocarbon (Ah) receptor, and certain kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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