Thermo Fisher Scientific TCAP Monoclonal Antibody (OTI8E6), TrueMAB
TCAP 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI8E6). Western blot에 적합하며 Human과 Mouse 시료에 반응. Lyophilized 형태로 제공되며 1 mg/mL 농도. Sarcomere 조립 관련 연구에 유용.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E6 |
| Immunogen | Full length human recombinant protein of human TCAP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that extends half the length of a sarcomere. Titin serves as a scaffold for myofibrils and muscle-related proteins.
TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1–Z2 domains and is a substrate of titin kinase—interactions critical to sarcomere assembly.
Mutations in the TCAP gene are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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