Thermo Fisher Scientific RBFOX2 Polyclonal Antibody
RBFOX2 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체. Western blot, IHC, ICC/IF에 적합하며 인간 단백질에 반응. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RBFOX2. Recombinant protein control fragment (Product # RP-91544). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646361 |
Product Specific Information
Immunogen sequence:
PTTTPDAMVQ PFTTIPFPPP PQNGIPTEYG VPHTQDYAGQ TGEHNLTLYG STQAHGEQSS NSPSTQNGSL
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 94%
Target Information
The RBFOX2 gene is one of several human genes similar to the C. elegans gene Fox-1. It encodes an RNA-binding protein that regulates alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element downstream of many alternatively spliced exons, promoting inclusion of the alternative exon in mature transcripts. It also interacts with the estrogen receptor 1 transcription factor, regulating its transcriptional activity. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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