Thermo Fisher Scientific KCNIP2 Polyclonal Antibody
Thermo Fisher Scientific의 KCNIP2 Polyclonal Antibody는 인간, 생쥐, 랫트에 반응하며 Western blot과 IHC에 적합합니다. KCNIP2 단백질을 타겟으로 하며, 동결건조 형태로 제공됩니다. 연구용으로만 사용되며 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
| Miscellaneous PubMed (Misc) | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of mouse KCNIP2 (Potassium channel-interacting protein 2) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: KCNIP2
Target Information
Voltage-gated potassium (Kv) channels are key components of potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain, these channels prevent reverse-propagation of action potentials.
Found associated with Kv4 channels are calcium-binding proteins termed KChIPs (Kv channel interacting proteins). These small molecular weight proteins bind to the cytoplasmic amino termini of Kv4 alpha-subunits and modulate their function.
Known KChIPs include:
- KChIP1: expressed in the brain
- KChIP2: expressed in the brain, heart, and lung; has three isoforms (a, b, c)
- KChIP3: also known as calsenilin and DREAM, expressed in the brain and testis
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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