Thermo Fisher Scientific SARS-CoV-2 Spike Protein (S1/S2) Recombinant Rabbit Monoclonal Antibody (ARC2373)
SARS-CoV-2 스파이크 단백질(S1/S2)에 특이적인 재조합 토끼 단일클론 항체입니다. Western blot, IHC, ICC/IF, Flow, ELISA, IP 등 다양한 응용에 사용 가능합니다. 높은 특이성과 재현성을 제공하며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| Flow Cytometry (Flow) | 1:50–1:200 | - |
| ELISA | 1:1,000–1:5,000 | - |
| Immunoprecipitation (IP) | 1:50–1:200 | - |
| Functional Assay | - | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Hamster |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2373 |
| Immunogen | Recombinant fusion protein of SARS-CoV-2 Spike S1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.28 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2866698 |
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus that causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death. The CoV Spike (S) protein is crucial for viral attachment, fusion, and entry, and serves as a key target for antibody, inhibitor, and vaccine development.
The Spike protein receptor-binding domain (RBD, S-RBD) binds strongly to human and bat ACE2 receptors, exhibiting higher affinity than the SARS-CoV RBD. The S1 subunit (residues 14–685) contains the RBD responsible for ACE2 binding, while the S2 subunit (residues 686–1273) mediates membrane fusion. The full-length SARS-CoV-2 S protein consists of 1273 amino acids, including a signal peptide (residues 1–13) at the N-terminus. The extracellular domain (S-ECD) represents the external portion of the Spike protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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