Thermo Fisher Scientific H4K20me3 Monoclonal Antibody (JSM20), ChIP-Verified

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

ChIP assay (ChIP)

1-5 µg

-

Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

JSM20

Immunogen

A synthetic peptide corresponding to the amino terminus of histone H4 in which Lys20 is tri-methylated.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

248 µg/mL

Purification

purified

Storage buffer

10mM HEPES buffered saline, pH 7.5, with 150mM NaCl, 50% glycerol, 100µg/mL BSA

Contains

<0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2884049

Product Specific Information

Species predicted to react based on 100% sequence homology to Xenopus, Bovine, and Porcine.

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Target Information

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.