Thermo Fisher Scientific DFNA5 Monoclonal Antibody (A1H3)
DFNA5 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Human DFNA5 aa 34-214 영역을 면역원으로 제작됨. Western blot, IHC, ICC/IF, Flow Cytometry에 적합하며, Protein G 정제 및 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A1H3 |
| Immunogen | Recombinant protein within Human DFNA5 (aa 34–214) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890523 |
Target Information
DFNA5 (deafness, autosomal dominant 5), also known as ICERE-1, is a 496 amino acid protein expressed in cochlea tissue and various organs including placenta, brain, heart, liver, lung, and pancreas. It has two alternatively spliced isoforms, short and long.
Defects in DFNA5 cause non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of hearing loss resulting from damage to sound-processing structures in the brain.
The DFNA5 gene maps to human chromosome 7, which contains over 1,000 genes and represents nearly 5% of the human genome. Mutations in genes located on chromosome 7 are associated with disorders such as Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia, and Shwachman-Diamond syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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