Thermo Fisher Scientific SUPT6H Polyclonal Antibody
Thermo Fisher Scientific SUPT6H Polyclonal Antibody는 인간 SUPT6H 단백질을 인식하는 Rabbit IgG 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1553 and the C-terminus (residue 1583) of Human Suppressor of Ty 6 Homolog |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
Transcription elongation factor which binds histone H3 and plays a key role in the regulation of transcription elongation and mRNA processing. Enhances transcription elongation by RNA polymerase II (RNAPII) and is required for activation by the HIV-1 transcriptional activator Tat. Forms a complex with IWS1 and the C-terminal domain (CTD) of RNAPII subunit RPB1 (POLR2A), recruiting mRNA export factors and histone modifying enzymes such as SETD2 for proper mRNA splicing and elongation-coupled H3K36 methylation. Also regulates class-switch recombination and somatic hypermutation via H3K4me3 epigenetic marks on AICDA target loci, and promotes myogenic gene activation through KDM6A-mediated H3K27me3 demethylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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