Thermo Fisher Scientific RSK1 Polyclonal Antibody
RSK1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합. Jurkat cell lysate를 양성 대조로 권장. MAPK 경로 관련 연구에 유용하며, 고순도 항원 친화 크로마토그래피 정제 제품. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 2.5–10 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the carboxy terminus of human RPS6K1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157446 |
Product Specific Information
- A suggested positive control is Jurkat cell lysate.
- PA5-20134 can be used with blocking peptide PEP-0252.
Target Information
RPS6KA1 (RSK1) is a growth-factor regulated serine/threonine kinase involved in the MAPK cascade. It controls cellular proliferation and differentiation through phosphorylation of transcription factors. RPS6KA1 contains two nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signaling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants encoding different isoforms have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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