Thermo Fisher Scientific Villin Monoclonal Antibody (5E3B2)
Villin 단백질을 인식하는 mouse monoclonal antibody로, Western blot, IHC, Flow cytometry, ELISA에 적합합니다. 인간 시료에 반응하며, Protein G로 정제된 1 mg/mL 액상 형태입니다. Villin은 위장관 및 신장 미세융모의 세포골격 관련 단백질로, 암 표지 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5E3B2 |
| Immunogen | Purified recombinant fragment of human VIL1 (AA: 1–209) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4 °C for short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090904 |
Target Information
Villin is part of the cytoskeleton associated with the microvillar actin core bundle of gastrointestinal and renal brush border. It interacts with actin in a Ca²⁺ and phosphoinositide-regulated manner. Villin serves as a specific marker for adenocarcinomas of the gastrointestinal tract and pancreas, and is also expressed in some Merkel cell tumors and adenocarcinomas of the lung, prostate, ovary, and kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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