Thermo Fisher Scientific UFD1L Monoclonal Antibody (4F11A4)
Thermo Fisher Scientific의 UFD1L 단클론 항체(4F11A4)는 인간 UFD1L 단백질을 인식하며 WB, IHC, ICC, Flow, ELISA 등 다양한 어플리케이션에 적합합니다. 고순도 Protein G 정제 항체로 안정적인 신호 검출을 제공합니다. 연구용으로만 사용됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific UFD1L Monoclonal Antibody (4F11A4)
Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F11A4 |
| Immunogen | Purified recombinant fragment of human UFD1L (AA: 208–307) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090833 |
Target Information
Ubiquitin-mediated proteolysis involves transferring ubiquitin (Ub) to lysine residues on cellular proteins, leading to degradation by the 26S proteasome. The UFD1 protein, first identified in yeast S. cerevisiae, has a human homolog known as UFD1L. UFD1 attenuates degradation of Ub-fusions with specific amino acid substitutions at Gly76 through selective multiubiquitination. Mutations in the UFD1 gene are associated with CATCH22 syndrome, characterized by cardiac defects, cleft palate, and hypocalcemia, suggesting its role in developmental processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.