
Thermo Fisher Scientific MTHFD2 Polyclonal Antibody
MTHFD2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, Flow cytometry에 적합합니다. 인간 및 생쥐 시료에 반응하며, 미토콘드리아 단백질 분석에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Flow Cytometry (Flow) | 1:50–1:100 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human MTHFD2 aa 210–250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913265 |
Product Specific Information
- Positive Control: HL-60 cell lysate, 293T cell lysate, human colon carcinoma tissue, mouse kidney tissue, human tonsil carcinoma tissue, Daudi
- Subcellular Location: Mitochondrion
Target Information
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities.
The enzyme functions as a homodimer and requires magnesium and inorganic phosphate for activity. Formation of the enzyme–magnesium complex allows NAD binding.
Alternative splicing results in two transcripts, one protein-coding and one non-coding. A pseudogene is located on chromosome 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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