Thermo Fisher Scientific Phospho-Cdc6 (Ser54) Recombinant Rabbit Monoclonal Antibody (ARC1693)
Cdc6 단백질의 Ser54 인산화 상태를 특이적으로 인식하는 재조합 토끼 단클론 항체입니다. Western blot과 ELISA에 적합하며, 높은 특이성과 재현성을 제공합니다. HEK293 세포에서 발현되었으며, PBS/glycerol 완충액 형태로 제공됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1693 |
| Immunogen | A synthetic phosphorylated peptide around S54 of human Cdc6 (Q99741) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898153 |
Product Specific Information
- Positive Samples: NIH/3T3
- Immunogen sequence: PLSPR
Target Information
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in the cell nucleus during the G1 phase of the cell cycle but translocates to the cytoplasm at the start of the S phase. The subcellular translocation of this protein during the cell cycle is regulated through its phosphorylation by Cdks. Transcription of this protein is regulated in response to mitogenic signals through transcriptional control mechanisms involving E2F proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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