Thermo Fisher Scientific GREM1 Recombinant Rabbit Monoclonal Antibody (117)

Applications

ELISA (ELISA)

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. To prevent contamination, it is recommended to add sodium azide (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The specific antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to the large rabbit immune repertoire

This antibody has specificity for Mouse GREM1.

Target Information

In Xenopus, Gremlin belongs to a novel gene family that acts as BMP antagonists in embryonic explants.
The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13–q15.
DRM-specific mRNA is expressed in various human tissues, including brain, ovary, intestine, and colon.
Down-regulation of DRM has been associated with tumor progression, supporting the hypothesis that human DRM plays an important role in both neuroembryological development and carcinogenesis.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.