Thermo Fisher Scientific GREM1 Recombinant Rabbit Monoclonal Antibody (117)
Recombinant rabbit monoclonal antibody specific for Mouse GREM1. ELISA에 최적화된 고특이성 항체로, 로트 간 일관성과 높은 민감도를 제공합니다. 방부제 무첨가 포뮬레이션으로 연구용에 적합하며, 장기 보관 시 -20°C에서 안정적입니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 117 |
| Immunogen | Recombinant Mouse GREM1 protein (Met1–Asp184) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786799 |
Product Specific Information
This product is preservative-free. To prevent contamination, it is recommended to add sodium azide (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The specific antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the large rabbit immune repertoire
This antibody has specificity for Mouse GREM1.
Target Information
In Xenopus, Gremlin belongs to a novel gene family that acts as BMP antagonists in embryonic explants.
The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13–q15.
DRM-specific mRNA is expressed in various human tissues, including brain, ovary, intestine, and colon.
Down-regulation of DRM has been associated with tumor progression, supporting the hypothesis that human DRM plays an important role in both neuroembryological development and carcinogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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