Thermo Fisher Scientific IFITM3 Polyclonal Antibody, Biotin
IFITM3 단백질을 인식하는 Biotin 결합 토끼 다클론 항체. Western blot, IHC, ELISA, IP에 적합. Human 시료 반응성. Affinity chromatography로 정제되었으며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1–50 of human Interferon-induced transmembrane protein 3 (IFITM3) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IFITM3 (Interferon Induced Transmembrane Protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein belonging to the IFITM family. These proteins are induced by type I and II interferons and contain multiple interferon-stimulated response elements (ISREs) in their promoters. IFITM proteins are involved in various cellular processes, including anti-proliferative activities and homotypic cell adhesion. They are often upregulated in cancer cells, suggesting a potential role in carcinogenesis. IFITM3 is a 133-amino acid membrane protein induced by IFN-α and IFN-γ, and its expression can be regulated by TEF-1, Brg-1, and Sp1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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