Thermo Fisher Scientific ATF1 Monoclonal Antibody (OTI2B4)
ATF1 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot 및 IHC(Paraffin)에 적합합니다. 1 mg/mL 농도의 액상형 제품이며 PBS, BSA, glycerol buffer에 보관됩니다. Human 반응성으로 연구용으로만 사용됩니다.
- 카탈로그번호
- MA526899
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B4 |
| Immunogen | Full length human recombinant protein of ATF1 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723935 |
Target Information
This gene encodes an activating transcription factor belonging to the ATF subfamily and bZIP (basic-region leucine zipper) family. It regulates the expression of downstream target genes related to growth, survival, and other cellular activities.
Phosphorylation at serine 63 by various kinases enhances transactivation and transcriptional activities, promoting cell transformation.
Fusion events involving this gene and FUS (chromosome 16) or EWSR1 (chromosome 22) generate chimeric proteins found in angiomatoid fibrous histiocytoma and clear cell sarcoma.
A pseudogene exists on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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