Thermo Fisher Scientific MEF2D Monoclonal Antibody (OTI1E11)
MEF2D 단백질을 인식하는 마우스 단클론 항체로 Western blot 및 IHC(P)에서 검증됨. 인간 시료에 반응하며, 비결합형 액상 형태로 제공. 1 mg/mL 농도, PBS 기반 완충액에 보관. 근육 및 신경 세포 분화 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–282 of MEF2D produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724669 |
Target Information
The MEF2D gene belongs to the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family regulate muscle and neuronal cell differentiation and development and are modulated by class II histone deacetylases.
Fusions of MEF2D with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) have been identified in acute lymphoblastic leukemia cell lines, suggesting a potential role in leukemogenesis. The encoded protein is also implicated in Parkinson’s disease and myotonic dystrophy.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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