Thermo Fisher Scientific WWOX Polyclonal Antibody
WWOX 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 생쥐, 랫트 시료에 반응하며 ELISA 및 Dot blot에 사용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체로, 연구용으로만 사용됨.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA (ELISA) | 1:10,000–1:100,000 |
| Dot blot (DB) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris glycine, pH 7.4–7.9, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% Sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2216366 |
Product Specific Information
PA1-31218 detects WWOX2 from human, rat, and mouse samples.
Target Information
WW domain-containing proteins are found in all eukaryotes and play an important role in regulating various cellular functions such as protein degradation, transcription, and RNA splicing.
This gene encodes a protein containing two WW domains and a short-chain dehydrogenase/reductase domain (SRD).
Highest normal expression is detected in hormonally regulated tissues such as testis, ovary, and prostate, suggesting a role in steroid metabolism.
The encoded protein shares over 90% identity with the mouse homolog, an essential mediator of TNF-α-induced apoptosis, implying a similar role in human apoptosis.
Evidence also suggests that this gene acts as a tumor growth suppressor. Alternative splicing generates transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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