Thermo Fisher Scientific RAB8B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

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Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2664303

Product Specific Information

Immunogen sequence: SSANVEEAFFT LARDIMTKLN RKMNDSNSAG AGGPVKITEN RSKKTSFFRC SLL

Highest antigen sequence identity to the following orthologs - mouse 94%, rat 94%.

Target Information

The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab superfamilies exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. Rab 8B (Ras-related protein Rab-8B) is a 207 amino acid lipid anchor that localizes to the cytoplasmic side of the cell membrane and belongs to the Rab family and small GTPase superfamily. Rab 8B may be involved in neurotransmitter release and vesicular trafficking, and is encoded by a gene located on human chromosome Rab 8B and mouse chromosome 9 C.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.