Thermo Fisher Scientific IL-2 Monoclonal Antibody (8D5)

Thermo Fisher Scientific IL-2 Monoclonal Antibody (8D5)

Applications and Tested Dilution

• Western Blot (WB): 1:500–1:2,000
• ELISA: 1:10,000

Product Specifications

Product Specific Information

MA5-17097 targets IL-2 in indirect ELISA and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of IL-2 expressed in E. coli.
MA5-17097 detects IL-2, which has a predicted molecular weight of approximately 17.6 kDa.

Target Information

Interleukin 2 (IL-2) is an immunomodulatory cytokine crucial for the proliferation of activated T cells and differentiation of B cells, NK cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric complex whose gamma chain is shared by IL-4 and IL-7.
Expression of the IL-2 gene in mature thymocytes is monoallelic, indicating a unique regulatory mechanism for single-gene expression.
Disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease, suggesting its essential role in immune response to antigenic stimuli.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.