Thermo Fisher Scientific SERPINC1 Monoclonal Antibody (7E11)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

ELISA (ELISA)

1:32,000

-

Product Specifications

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

7E11

Immunogen

Antithrombin III isolated from human plasma.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.05 mg/mL

Storage conditions

4° C, store in dark

Shipping conditions

Wet ice

RRID

AB_1070421

Product Specific Information

HYB 230-04-02 is specific for human AT III, native form.

HYB 230-04-02 has been successfully used in ELISA and Western blot procedures. Molecular weight 58kDa

The HYB 230-04-02 immunogen is AT III, native form, found in human cells.

Target Information

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.