Thermo Fisher Scientific PCPTP1 Polyclonal Antibody
Thermo Fisher Scientific의 PCPTP1 Polyclonal Antibody는 Rabbit IgG 기반의 다클론 항체로, Mouse 시료에 반응합니다. Western blot과 ELISA에 적합하며, 세포 성장 및 분화 관련 PTP 신호 전달 연구에 활용됩니다. 액상 형태로 -20°C 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 240–400 of human PTPRR (NP_0028402) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804852 |
Product Specific Information
- Immunogen sequence:
IIVTCLMILY RLKERFQLSL RQDKEKNQEI HLSPITLQPA LSEAKTVHSM VQPEQAPKVL NVVVDPQGRG APEIKATTAT SVCPSPFKMK PIGLQERRGS NVSLTLDMSS LGNIEPFVSI PTPREKVAME YLQSASRILT RSQLRDVVAS SHLLQSEFME I - Positive Samples: Mouse liver
- Cellular Location: Cell membrane, Cytoplasm, Single-pass type I membrane protein, perinuclear region
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates diverse cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation. This receptor-type PTP has extracellular, transmembrane, and intracellular catalytic domains. The mouse homolog is mainly expressed in the brain and interacts with MAP kinases, influencing their activity and localization. The rat counterpart is regulated by nerve growth factor, suggesting a role in neuronal growth and differentiation.
⚠ WARNING:
This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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