Thermo Fisher Scientific Perforin-1 (Pore Forming Protein) (Apoptosis Marker) Recombinant Rabbit Monoclonal Antibody (PRF1/8662R)
Recombinant rabbit monoclonal antibody against Perforin-1 (PRF1/8662R). Human reactive apoptosis marker for IHC applications. High purity (Protein A/G purified), 200 µg/mL in PBS with BSA. Suitable for cytotoxic lymphocyte and tumor immunology research.
- 카탈로그번호
- 5551-RBM9-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Perforin-1 (Pore Forming Protein) (Apoptosis Marker) Recombinant Rabbit Monoclonal Antibody (PRF1/8662R)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PRF1/8662R |
| Immunogen | Recombinant human Perforin-1 protein fragment (aa 413–552) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Perforin is a major cytolytic protein found in cytolytic granules and plays a critical role in immune defense against tumors and viral infections. It is a 555 amino acid protein (70–75 kDa) with a 21 amino acid signal peptide. Perforin forms transmembrane pores in target cells, similar to complement component C9. It is expressed in cytotoxic T lymphocytes and natural killer cells, but not in helper T cells or other tumor cell types. Mutations in the perforin gene are associated with familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare autosomal recessive disorder in early childhood. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.