Thermo Fisher Scientific MUPP1 Polyclonal Antibody
Rabbit 유래 다클론 항체로, MUPP1 단백질 검출에 사용됩니다. Western blot 및 Immunoprecipitation에 적합하며, 4°C에서 보관합니다. 액상 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 775 and 825 of human Multiple PDZ Domain Protein (MUPP1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
MUPP1 (multi PDZ domain protein 1, MPDZ) was discovered as an interacting partner with the 5-HT2C receptor and co-localizes with 5-HT2A or 5-HT2C receptors in all regions of the mouse brain, including the choroid plexus.
MUPP1 contains 13 PDZ domains but no apparent catalytic domain. It is concentrated in tight junctions of polarized epithelial cells and binds to claudin-1 and junctional adhesion molecule (JAM).
MUPP1 may function as a multivalent scaffold protein that recruits various proteins to tight junctions and also interacts with claudin-8, suggesting a role in tight junction barrier function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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