Thermo Fisher Scientific Calreticulin Polyclonal Antibody
Calreticulin 단백질을 검출하는 Thermo Fisher Scientific의 다클론 항체입니다. Western blot, ICC/IF 등 다양한 응용에 사용 가능하며, 여러 종(인간, 생쥐 등)에 반응합니다. 항원 친화 크로마토그래피로 정제된 액상 형태로, 안정적 저장이 가능합니다.
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Thermo Fisher Scientific Calreticulin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 4 publications |
| Immunohistochemistry (IHC) | - | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 2 publications |
| Immunocytochemistry (ICC/IF) | Assay-dependent | View 5 publications |
| Flow Cytometry (Flow) | - | View 3 publications |
| Immunoprecipitation (IP) | - | View 1 publication |
| Neutralization (Neu) | - | View 1 publication |
| Fluorescence Resonance Energy Transfer (FRET) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Hamster, Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic Peptide: K(24) E Q F L D G D A W T N R W V E S K H K(43) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2069607 |
Product Specific Information
PA1-902A detects calreticulin from canine, hamster, human, mouse, and rat tissues.
It has been successfully used in Western blot, immunocytochemistry, and immunofluorescence procedures.
By Western blot, this antibody detects an approximately 60–66 kDa protein representing calreticulin.
The immunizing peptide corresponds to amino acid residues 24–43 from mouse calreticulin.
PA1-902A immunizing peptide (Cat. # PEP-018) is available for use in neutralization and control experiments.
Target Information
Calr (Calreticulin) is a calcium-binding chaperone that promotes folding, oligomeric assembly, and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle.
Calr interacts transiently with most monoglucosylated glycoproteins synthesized in the ER and with the DNA-binding domain of NR3C1 to mediate its nuclear export.
It may also play a role in maternal gene expression regulation and oocyte maturation through calcium homeostasis regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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