Thermo Fisher Scientific Calreticulin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

-

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

-

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

-

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 5 publications 5 publications

Flow Cytometry (Flow)

-

View 3 publications 3 publications

Immunoprecipitation (IP)

-

View 1 publication 1 publication

Neutralization (Neu)

-

View 1 publication 1 publication

Fluorescence Resonance Energy Transfer (FRET)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Dog, Hamster, Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Chicken / IgY

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic Peptide: K(24) E Q F L D G D A W T N R W V E S K H K(43). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Calreticulin,uniProtId:P14211-1,ncbiNodeId:10090,antigenRange:24-43,antigenLength:416,antigenImageFileName:PA1-902A_Calreticulin_P14211-1_Chicken.svg,antigenImageFileNamePDP:PA1-902A_Calreticulin_P14211-1_Chicken_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2069607

Product Specific Information

PA1-902A detects calreticulin from canine, hamster, human, mouse and rat tissues.

PA1-902A has been successfully used in Western blot, immunocytochemistry and immunofluorescene procedures. By Western blot, this antibody detects an ~60-66 kDa protein representing calreticulin.

PA1-902A immunizing peptide corresponds to amino acid residues 24-43 from mouse calreticulin. PA1-902A immunizing peptide (Cat. # PEP-018) is available for use in neutralization and control experiments.

Target Information

Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.