Thermo Fisher Scientific CD3g Polyclonal Antibody
Rabbit polyclonal antibody targeting human CD3 gamma protein for WB, IHC, and Flow applications. High specificity and affinity purified. Suitable for T-cell receptor complex studies. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Flow Cytometry (Flow) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 106–182 of Human CD3 gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris Glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546863 |
Product Specific Information
- Recommended positive controls: Molt-4, Raji
- Predicted reactivity: Pig (100%), Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta, and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex.
This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
The genes encoding the epsilon, gamma, and delta polypeptides are located in the same cluster on chromosome 11.
Defects in the CD3G gene are associated with T-cell immunodeficiency.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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