
Thermo Fisher Scientific Human MAPK13 (p38 delta), His Tag Recombinant Protein
인간 MAPK13(p38 delta) 재조합 단백질로 세린/트레오닌 키나아제 활성 연구에 적합. Baculovirus 발현 시스템 사용, His-tag 부착, 고순도 정제. 스트레스 반응 및 세포 분화 연구용. -80°C 보관 권장.
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Applications
- Kinase Assay (KA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Baculovirus |
| Amino Acid Sequence | Full length |
| Tag | His-tag |
| Molecular Weight | 46.2 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris (pH 7.5), 0.02% Triton X-100, 50% glycerol, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- For maximum recovery, please spin prior to use.
- Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material in original packaging until exhausted.
- For larger sizes, prepare aliquots to reduce freeze/thaw cycles (aliquots below 20 µL not recommended).
- Do not store diluted kinase.
- Properly stored at -80°C, product guaranteed for 6 months from date of purchase.
- Protein Form: Full Length
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces extracellular signals related to cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by stress and proinflammatory cytokines through phosphorylation by MAP kinase kinases or autophosphorylation via MAP3K7IP1/TAB1 interaction. Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, indicating roles in stress-related transcription, cell cycle regulation, and genotoxic stress response. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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