Thermo Fisher Scientific Kappa Light Chain Monoclonal Antibody (L1C1)
인간 Kappa Light Chain을 인식하는 마우스 단클론 항체로, IHC 및 Flow Cytometry에 적합합니다. Protein A로 정제된 액상 형태이며, 0.5 mg/mL 농도로 제공됩니다. 백혈병 및 림프종 등의 연구용으로 유용합니다.
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Thermo Fisher Scientific Kappa Light Chain Monoclonal Antibody (L1C1)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Flow Cytometry (Flow) | 0.5–5 µg/10^6 cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | L1C1 |
| Immunogen | Immunoglobulin kappa light chain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human tonsil lysate
- Cellular location: Cytoplasmic and Secreted
Target Information
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa).
Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region.
The ratio of kappa to lambda is 70:30.
Antibodies to the kappa light chain are useful in identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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