Thermo Fisher Scientific Kappa Light Chain Monoclonal Antibody (K88)
인간 Kappa 경쇄를 인식하는 단클론 항체로, IHC(P) 및 유세포분석에 적합합니다. 단백질 A로 정제된 액상 항체이며, 0.5 mg/mL 농도로 제공됩니다. 백혈병, 형질세포종, 림프종 연구에서 클론성 확인에 유용합니다. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Flow Cytometry (Flow) | 0.5–5 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | K88 |
| Immunogen | Immunoglobulin kappa light chain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human tonsil lysate
- Cellular location: Cytoplasmic and Secreted
Target Information
Immunoglobulin classes share a basic structure of four polypeptide chains — two heavy chains (five types) and two light chains (kappa, lambda; both ~22.5 kDa).
Kappa and lambda chains consist of variable and constant regions, distinguishable by antigenic properties of the constant region.
The kappa to lambda ratio is approximately 70:30.
Antibodies to the kappa light chain are useful in identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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