Thermo Fisher Scientific SCAMP2 Monoclonal Antibody (OTI2F3), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:4,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Secretory carrier membrane proteins (SCAMPs) are components of post-Golgi membranes involved in membrane trafficking.
In fibroblasts, SCAMPs localize to compartments responsible for receptor recycling and endocytosis.
In neurons, SCAMPs associate with synaptic vesicles, secretion granules, and transporter vesicles.
SCAMPs possess four transmembrane regions and a cytoplasmic tail.
Of the five known SCAMPs, SCAMPs 1–3 contain N-terminal NPF repeats interacting with EH domain proteins, whereas SCAMPs 4 and 5 lack these repeats.
SCAMPs 1–4 are ubiquitously expressed, while SCAMP5 is brain-specific and expressed late in development, coinciding with mature synapse formation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.