Thermo Fisher Scientific IL10RA Monoclonal Antibody (OTI1G10), TrueMAB
인간 IL10RA 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 Immunocytochemistry에 적합. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 연구용으로 면역억제 신호전달 및 세포 생존 경로 분석에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G10 |
| Immunogen | Full length human recombinant protein of human IL10RA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The IL10RA gene encodes a receptor for interleukin 10, structurally related to interferon receptors.
It mediates the immunosuppressive signal of interleukin 10, inhibiting synthesis of proinflammatory cytokines.
This receptor promotes survival of progenitor myeloid cells via the IRS-2/PI3K/AKT pathway and activates JAK1 and TYK2 kinases through tyrosine phosphorylation.
Two transcript variants have been identified: one protein-coding and one non-coding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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