
Thermo Fisher Scientific TOLLIP Monoclonal Antibody (OTI1D1), TrueMAB
TOLLIP 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1D1). Western blot 검증 완료. HEK293T 세포에서 발현된 full-length human TOLLIP 단백질을 면역원으로 사용. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D1 |
| Immunogen | Full-length human recombinant TOLLIP protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.3) with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Toll-like receptors (TLRs) are conserved pattern-recognition molecules that mediate antimicrobial responses. They recognize microbial products and link innate and adaptive immunity. TLRs activate kinases and transcription factors through adaptor molecules such as TOLLIP, MyD88, and TRIF.
TOLLIP associates with TLR2 and TLR4, acting as an inhibitor of TLR activation and regulating proinflammatory mediator production during infection and inflammation.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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