Thermo Fisher Scientific GABA(A) beta 3 Receptor Polyclonal Antibody
GABA(A) beta 3 수용체를 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 동결 조직 면역조직화학에 적합. 고순도 항원 친화 크로마토그래피 정제. 신경전달 억제 연구용으로 사용 가능.
- 카탈로그번호
- AGA-013-xxxxx (3개 옵션)
- 판매단위
- pk
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Thermo Fisher Scientific GABA(A) beta 3 Receptor Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)GRYMGDRSIPHKK, corresponding to amino acid residues 413–425 of rat GABRB3, 2nd intracellular loop |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW) depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and keep at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter found throughout the central nervous system.
GABA is formed by decarboxylation of glutamate, resulting in two receptor types: GABA-A and GABA-B.
Binding of GABA to GABA-A receptors increases chloride ion influx into neurons, leading to signal repression.
Deficiency in GABA-mediated signaling may cause uncontrolled neuronal activity, leading to blackouts, rapid muscle contractions, seizures, and epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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