Thermo Fisher Scientific CCNG1 Polyclonal Antibody, MaxPab
Cyclin G1 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, Western blot 및 면역세포화학(ICC/IF)에 적합합니다. 인간 시료에 반응하며, PBS(pH 7.4) 용액 내 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관 권장됩니다.
- 카탈로그번호
- H00000900-B01P
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CCNG1 (NP_004051.1, 1–295 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MIEVLTTTDS QKLLHQLNAL LEQESRCQPK VCGLRLIESA HDNGLRMTAR LRDFEVKDLL SLTQFFGFDT ETFSLAVNLL DRFLSKMKVQ PKHLGCVGLS CFYLAVKSIE EERNVPLATD LIRISQYRFT VSDLMRMEKI VLEKVCWKVK ATTAFQFLQL YYSLLQENLP LERRNSINFE RLEAQLKACH CRIIFSKAKP SVLALSIIAL EIQAQKCVEL TEGIECLQKH SKINGRDLTF WQELVSKCLT EYSSNKCSKP NVQKLKWIVS GRTARQLKHS YYRITHLPTI PEMVP
Target Information
Cyclins are regulatory subunits of Cdc2 p34 and related cyclin-dependent kinases (Cdks) that play critical roles in cell cycle progression.
- Cyclin A and B form complexes with Cdc2 p34 kinase to control G2 to M transition and S phase progression.
- G1 cyclins regulate the G1 to S transition, with Cyclin D1 interacting with Cdk2, Cdk4, and Cdk5.
- Cyclin E and Cdk2 interact during the G1 to S transition.
- Cyclin G contains an N-terminal cyclin box and a C-terminal domain homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor.
- Cyclin G expression is induced within 3 hours after growth stimulation and remains elevated without cell cycle dependency.
- Cyclin G2 shares 53% sequence identity with Cyclin G1, with peak expression in late S phase, whereas Cyclin G1 expression is constitutive.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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