
Thermo Fisher Scientific Toralizumab Chimeric Recombinant Rabbit Monoclonal Antibody (IDEC-131 (Toralizumab))
Human CD40 ligand 특이적 비작용성 키메릭 재조합 토랄리주맙 단클론 항체. HEK293 세포에서 발현된 Rabbit IgG, kappa 형식. 면역세포 염색 및 억제 분석에 적합하며, 염증 및 조직 손상 관련 연구용으로 사용 가능.
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Applications
- Immunocytochemistry (ICC/IF): Tested dilution 10 µg/mL
- Inhibition Assays (IA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | IDEC-131 (Toralizumab) |
| Immunogen | Soluble fusion protein of human gp39 (gp39-CD8) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_3074752 |
Product Specific Information
Specificity: This antibody is a non-agonistic antibody specific for human CD40 ligand.
Target Information
Toralizumab binds to interferon gamma, preventing its interaction with immune cell receptors. This inhibition blocks downstream signaling pathways responsible for inflammation and tissue damage in autoimmune diseases. By blocking interferon gamma, toralizumab helps reduce inflammation and prevent further tissue damage.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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