Thermo Fisher Scientific Toralizumab Chimeric Recombinant Rabbit Monoclonal Antibody (IDEC-131 (Toralizumab))

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

10 µg/mL

-

Inhibition Assays (IA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

IDEC-131 (Toralizumab)

Immunogen

The original monoclonal antibody was generated by immunization with a soluble fusion protein of human gp39 (gp39-CD8).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3074752

Product Specific Information

Specificity: This antibody is a non agonistic antibody specifc for human CD40 ligand.

Target Information

Toralizumab works by binding to interferon gamma, which prevents it from interacting with its receptors on immune cells. This blocks the downstream signaling pathways that lead to inflammation and tissue damage in autoimmune diseases. By blocking interferon gamma, toralizumab aims to reduce inflammation and prevent further tissue damage in affected individuals.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.