Thermo Fisher Scientific NKCC1 Polyclonal Antibody
Rabbit polyclonal antibody targeting NKCC1 (SLC12A2), suitable for IHC in multiple species. Affinity-purified, unconjugated, 1 mg/mL in PBS with sodium azide. Enables study of sodium/chloride transport and cellular ionic balance. For research use only.
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Thermo Fisher Scientific NKCC1 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Horse, Guinea pig, Human, Mouse, Non-human primate, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from internal region of human SLC12A2 / NKCC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551549 |
Target Information
NKCC1 mediates sodium and chloride transport and reabsorption. It is a membrane protein important for maintaining proper ionic balance and cell volume. NKCC1 functions as an electrically silent transporter system and is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been identified for NKCC1. Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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