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Thermo Fisher Scientific S1P1 Recombinant Rabbit Monoclonal Antibody (4F2)
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S1P1 단백질을 인식하는 토끼 유래 재조합 단클론 항체입니다. Western blot에 최적화되어 있으며, 인간 시료에 반응합니다. 고순도의 친화 크로마토그래피 정제 항체로, 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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마지막 업데이트 2025. 07. 25. 오후 10:52
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Thermo Fisher Scientific MA538397 S1P1 Recombinant Rabbit Monoclonal Antibody (4F2) 100 ul pk판매 단위 pk ·
재고 확인 필요
743,900원VAT 포함 818,290원
Thermo Fisher Scientific · Thermo Fisher Scientific S1P1 Recombinant Rabbit Monoclonal Antibody (4F2)
Applications
- Western Blot (WB): 1:500–1:5,000
- Tested in direct-ELISA
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4F2 |
| Immunogen | A synthesized peptide derived from human EDG1 (aa 7–21) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.44 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898311 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
S1P1 is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P), coupled to the G(i) subclass of heteromeric G proteins.
S1P1 signaling activates RAC1, SRC, PTK2/FAK1, and MAP kinases, playing a key role in:
- Cell migration via actin cytoskeleton reorganization
- Lamellipodia formation in response to SPHK1 activity
- Normal chemotaxis toward S1P
- Embryonic heart development and cardiac morphogenesis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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